Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429924 | 0.86 | KDM4E (0.33) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL13345556 | 0.84 | KDM4E (0.32) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL428566 | 0.83 | KDM4E (0.32) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL430432 | 0.82 | LMNA (0.35) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL428564 | 0.80 | KDM4E (0.33) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL464644 | 0.78 | MAPT (0.48) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL430381 | 0.78 | MAPT (0.48) | KDM4ELMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL429932 | 0.76 | MAOA (0.41) | KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL10280577 | 0.73 | MAPT (0.48) | LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL428525 | 0.73 | MAPT (0.48) | LMNAMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-20120065064-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065064-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP4X1 | KDM4E 1210/4885LMNA 4565/4885GAA 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.