Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276103 | 0.87 | TDP1 (0.35) | TDP1CYP3A4MAPT | |
| SCHEMBL6033622 | 0.85 | TDP1 (0.33) | TDP1CYP3A4MAPT | |
| SCHEMBL7050191 | 0.77 | — | — | |
| SCHEMBL28045734 | 0.76 | KDM4E (0.32) | MAPT | |
| SCHEMBL7499659 | 0.74 | KDM4E (0.35) | MAPT | |
| SCHEMBL25619798 | 0.74 | KDM4E (0.33) | TDP1MAPT | |
| SCHEMBL13732851 | 0.72 | TDP1 (0.35) | TDP1CYP3A4MAPT | |
| SCHEMBL2875077 | 0.70 | LMNA (0.45) | MAPT | |
| SCHEMBL31295759 | 0.70 | KDM4E (0.38) | TDP1MAPT | |
| SCHEMBL31347383 | 0.69 | EGLN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155448-A1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |