Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 3/20 | 0.34 |
| ▸ | CELA1 | Q9UNI1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502910 | 0.81 | KDM4E (0.33) | KDM4EHSD17B10HTTMAPTTP53 | |
| SCHEMBL9731091 | 0.78 | ABCB11 (0.37) | KDM4EHSD17B10HTTMAPTTP53 | |
| SCHEMBL27638747 | 0.76 | NPSR1 (0.35) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL11015197 | 0.69 | KDM4E (0.33) | KDM4EHSD17B10HTTMAPTTP53 | |
| SCHEMBL27774251 | 0.67 | PREP (0.33) | KDM4EHSD17B10HTTMAPTTP53 | |
| SCHEMBL27996882 | 0.67 | ABCB11 (0.33) | KDM4EHSD17B10HTTMAPTTP53 | |
| SCHEMBL20075881 | 0.67 | PREP (0.44) | KDM4EHSD17B10HTTMAPTTP53 | |
| SCHEMBL276103 | 0.66 | TDP1 (0.35) | MAPTPOLB | |
| SCHEMBL5494945 | 0.65 | HTT (0.37) | KDM4EHSD17B10HTTMAPTGAA | |
| SCHEMBL28799037 | 0.65 | SMN1; SMN2 (0.34) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634405-B1 | Pyrimidinyl acrylic acid derivatives, process for their preparation and their use for the control of phytopathogens | BAYER AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| US-5635508-A | FUNGICIDES | NOVARTIS AG (CH) | 1997-06-03 | — | — | US | disclosed |
| CN-1122800-A | Pyrimidinyl acrylic acid derivatives | SANDOZ LTD (CH) | 1996-05-22 | — | — | CN | disclosed |
| US-5453427-A | Control phytopathogenic fungi especially in monocotelydons, podery mildew and rust | SANDOZ LTD. (CH) | 1995-09-26 | — | — | US | disclosed |
| EP-0634405-A1 | Pyrimidinyl acrylic acid derivatives, process for their preparation and their use for the control of phytopathogens | SANDOZ LTD. (CH) | 1995-01-18 | — | — | EP | disclosed |