⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341058 | 0.81 | — | — | |
| SCHEMBL8681187 | 0.77 | CYP1A2 (0.39) | — | |
| SCHEMBL2122700 | 0.76 | CES2 (0.37) | — | |
| SCHEMBL7533513 | 0.74 | TSHR (0.34) | — | |
| SCHEMBL536763 | 0.73 | — | — | |
| SCHEMBL300224 | 0.71 | — | — | |
| SCHEMBL59903 | 0.71 | — | — | |
| SCHEMBL8894517 | 0.71 | — | — | |
| SCHEMBL114222 | 0.71 | — | — | |
| SCHEMBL9719198 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 979 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391815-A1 | EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2023-12-07 | — | — | US | claimed |
| US-11746123-B2 | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2023-09-05 | — | — | US | claimed |
| US-11242364-B1 | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof | ChromaDex Inc. (US) | 2022-02-08 | — | — | US | claimed |
| US-20210347806-A1 | EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2021-11-11 | — | — | US | claimed |
| US-10689411-B2 | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2020-06-23 | — | — | US | claimed |
| CN-110662542-A | Efficient and scalable synthesis of nicotinyl nucleosides and reduced nicotinyl nucleosides, modified derivatives thereof, phosphorylated analogs thereof, adenosine dinucleotide conjugates thereof, and novel crystalline forms thereof | 英国贝尔法斯特女王大学 | 2020-01-07 | — | — | CN | claimed |
| EP-3538099-A1 | EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF | The Queen's University of Belfast (GB) | 2019-09-18 | — | — | EP | claimed |
| EP-3429354-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | Chromadex Inc. (US) | 2019-01-23 | — | — | EP | claimed |
| US-10000520-B2 | B-vitamin and amino acid conjugates ofnicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof | ChromaDex Inc. (US) | 2018-06-19 | — | — | US | claimed |
| US-9975915-B1 | Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-22 | — | — | US | claimed |
| EP-0857173-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-08-12 | — | — | EP | claimed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | claimed |
| EP-0765160-A4 | — | — | 1997-04-09 | — | — | EP | claimed |
| EP-0765160-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY, AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 1997-04-02 | — | — | EP | claimed |
| WO-1997000884-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | claimed |
| WO-1995020958-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 1995-08-10 | — | — | WO | claimed |
| US-5169839-A | DERIVATIVES OF 3'- AND 3\"-O-DESMETHYL AVERMECTIN COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING MELMINTIC AND PARASITIC INFECTIONS | MERCK & CO., INC. (US) | 1992-12-08 | — | — | US | claimed |
| EP-0456509-A1 | Derivatives of 3' - and 3\"-0-desmethyl avermectin compounds | MERCK & CO. INC. (US) | 1991-11-13 | — | — | EP | claimed |
| EP-0375395-A2 | Derivatives of 3'-and 3\"-0-desmethyl avermectin compounds | MERCK & CO. INC. (US) | 1990-06-27 | — | — | EP | claimed |
| US-4080303-A | VISCOSITY IMPROVER | THE LUBRIZOL CORPORATION (US) | 1978-03-21 | — | — | US | claimed |