⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937782 | 0.97 | — | — | |
| SCHEMBL563582 | 0.81 | — | — | |
| SCHEMBL2442929 | 0.79 | — | — | |
| SCHEMBL1401237 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL3980051 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL7382880 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL3972155 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL970516 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL1654498 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL374773 | 0.77 | TSHR (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230102146-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | SHENZHEN NEPTUNUS PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2023-03-30 | — | — | US | claimed |
| EP-4108666-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | Shenzhen Neptunus Pharmaceutical Research Institute Co., Ltd. (CN) | 2022-12-28 | — | — | EP | claimed |
| CN-113336768-B | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2022-08-19 | — | — | CN | claimed |
| EP-3110452-B1 | BIOACTIVE AGENTS INCLUDED IN FUNCTIONALIZED STARCH HAVING A SINGLE HELIX V-STRUCTURE | B ORGANIC FILMS CORP (CA) | 2021-12-15 | — | — | EP | claimed |
| CN-113336768-A | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-107580596-B | Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-07-14 | — | — | CN | claimed |
| US-20200109144-A1 | Sulfonimidoylpurinone Compounds | HOFFMANN-LA ROCHE INC. (US) | 2020-04-09 | — | — | US | claimed |
| CN-108003136-B | Aminomethyl phenyl yl pyridines class compound and its application in DPP-4 enzyme inhibitor | 上海医药工业研究院 | 2019-09-13 | — | — | CN | claimed |
| US-20190031618-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-31 | — | — | US | claimed |
| US-10118900-B2 | Benzimidazole derivatives useful as CB-1 inverse agonists | JANSSEN PHARMACEUTICA NV (BE) | 2018-11-06 | — | — | US | claimed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | claimed |
| US-4659734-A | BACTERICIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| US-4619943-A | NEUROLEPTIC AGENTS | RAO KOPPAKA V | 1986-10-28 | — | — | US | claimed |
| EP-0121265-A2 | Method of heterogeneous reaction | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1984-10-10 | — | — | EP | claimed |
| US-4419522-A | ANTITUMOR AGENTS | CHINOIN GYOGYSZER VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-12-06 | — | — | US | claimed |
| EP-0040435-B1 | PEPTIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Eisai Co., Ltd. (JP) | 1983-07-20 | — | — | EP | claimed |
| US-4317827-A | 4-[4(or 3)-Acylaminophenyl]pyridines and their use as cardiotonics | STERLING DRUG INC. (US) | 1982-03-02 | — | — | US | claimed |
| EP-0040435-A1 | Peptide derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1981-11-25 | — | — | EP | claimed |
| US-3951964-A | Method for preparing azines | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-04-20 | — | — | US | claimed |
| US-3943132-A | Process for the preparation of hydrazones | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-03-09 | — | — | US | claimed |