SCHEMBL4288351

SCHEMBL4288351

CCCOC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26622081 0.87
SCHEMBL1145474 0.83
SCHEMBL9644539 0.81
SCHEMBL2335019 0.81
SCHEMBL173320 0.81
SCHEMBL23174998 0.81
SCHEMBL2032189 0.80
SCHEMBL10953427 0.79 CES2 (0.48)
SCHEMBL9802054 0.79 CES2 (0.48)
SCHEMBL4954643 0.79 CES2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117120476-A Antibodies specific for structurally disordered sequences XL-普洛坦公司 2023-11-24 CN claimed
EP-4267628-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-protein GmbH (DE) 2023-11-01 EP claimed
WO-2022136582-A1 ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES XL-PROTEIN GMBH (DE) 2022-06-30 WO claimed
US-20200282071-A1 CONJUGATES OF PROTEIN DRUGS AND P/A PEPTIDES XL-PROTEIN GMBH (DE) 2020-09-10 US claimed
EP-3641827-A1 CONJUGATES OF PROTEIN DRUGS AND P/A PEPTIDES XL-protein GmbH (DE) 2020-04-29 EP claimed
CN-110891612-A Conjugates of protein drugs and P/A peptides XL-蛋白有限责任公司 2020-03-17 CN claimed
WO-2018234455-A1 CONJUGATES OF PROTEIN DRUGS AND P/A PEPTIDES XL-PROTEIN GMBH (DE) 2018-12-27 WO claimed
US-20070078146-A1 Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma PHARMACIA CORPORATION 2007-04-05 US claimed
EP-1144403-B1 SUBSTITUTED PYRAZOLES AS P38 KINASE INHIBITORS SEARLE LLC (US) 2004-10-06 EP claimed
US-6617324-B1 Phenyl, cyclohexyl and pyridinyl or pyrimidinyl-substituted G. D. SEARLE & COMPANY 2003-09-09 US claimed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1144403-A1 SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS G.D. SEARLE & CO. (US) 2001-10-17 EP claimed
WO-2000031063-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. SEARLE & CO. (US) 2000-06-02 WO claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
US-4590209-A INOTROPIC, ANTIARRHYTHMIA, AND ANTILIPEMIC AGENTS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1986-05-20 US claimed
US-4551477-A ANTILIPEMIC AGENTS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1985-11-05 US claimed
EP-0000931-B1 ENZYMATIC CLEAVAGE OF N-ACYL-THIENAMYCINS MERCK & CO. INC. (US) 1982-04-14 EP claimed
US-4162193-A Enzymatic cleavage of N-acyl-thienamycins MERCK & CO., INC. (US) 1979-07-24 US claimed
EP-0000931-A1 Enzymatic cleavage of N-acyl-thienamycins MERCK & CO. INC. (US) 1979-03-07 EP claimed