Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288372 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4289246 | 0.92 | MAPT (0.71) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4289249 | 0.92 | MAPT (0.71) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4288409 | 0.85 | ALDH1A1 (0.73) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4288413 | 0.85 | ALDH1A1 (0.73) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4246818 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4241354 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4064914 | 0.76 | MAPT (0.40) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL4062560 | 0.76 | MAPT (0.98) | ALDH1A1MAPTHTTNPSR1LMNA | |
| Hydrochloric Acid SCHEMBL4290512 | 0.75 | MAPT (1.00) | ALDH1A1MAPTHTTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883504-B2 | Cell differentiation suppressing agent, method of culturing cells using the same, culture solution, and cultured cell line | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20090155906-A1 | CELL DIFFERENTIATION SUPPRESSING AGENT, METHOD OF CULTURING CELLS USING THE SAME, CULTURE SOLUTION, AND CULTURED CELL LINE | MIYABAYASHI TOMOYUKI | 2009-06-18 | — | — | US | disclosed |
| EP-1640449-A1 | CELL DIFFERENTIATION INHIBITING AGENT, CELL CULTURE METHOD USING THE SAME, CULTURE MEDIUM AND CULTURED CELL LINE | Asahi Kasei Kabushiki Kaisha (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-20050153941-A1 | Increasing Stage Specific Embryonic Antigen (SSEA) and Nanog gene levels; culturing a stem cell using a low molecular weight derivative of 2-(phenylazo)-2-(3,4-dihydro-2H-isoquinoline-1-ylidene) or N-phenylindole | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153941-A1 | Increasing Stage Specific Embryonic Antigen (SSEA) and Nanog gene levels; culturing a stem cell using a low molecular weight derivative of 2-(phenylazo)-2-(3,4-dihydro-2H-isoquinoline-1-ylidene) or N-phenylindole | MKI67, ALPG, NES | ALDH1A1 38/4885MAPT 4659/4885HTT 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.