Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4291116 | 0.99 | CYP19A1 (0.46) | CYP19A1GPR119KCNH2PPARDPPARA | |
| SCHEMBL4293515 | 0.86 | MEN1 (0.43) | GPR119KCNH2PARP1RENCA1 | |
| Hydrochloric Acid SCHEMBL4287634 | 0.85 | MEN1 (0.42) | GPR119KCNH2PARP1REN | |
| Hydrochloric Acid SCHEMBL4283218 | 0.81 | CYP2D6 (0.48) | CYP19A1CA1CA2CA9 | |
| SCHEMBL4285472 | 0.81 | CYP19A1 (0.48) | CYP19A1GPR119KCNH2PPARDPPARA | |
| SCHEMBL3493396 | 0.80 | TEAD1 (0.46) | PARP1RENCA1CA2CA4 | |
| SCHEMBL4282373 | 0.80 | L3MBTL1 (0.47) | PPARAPARP1CA1CA2CA4 | |
| SCHEMBL4751897 | 0.80 | L3MBTL1 (0.47) | PPARAPARP1CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4293711 | 0.79 | PARP1 (0.45) | PARP1RENCA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4293709 | 0.79 | PARP1 (0.45) | PARP1RENCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | CYP19A1 705/4885GPR119 310/4885KCNH2 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.