SCHEMBL4288684

SCHEMBL4288684

OCCCc1ccc(Cc2ccc(CO)cc2O)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.47
ACHE P22303 2/20 0.46
MAPT P10636 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ALOX5 P09917 3/20 0.43
CA2 P00918 1/20 0.42
IGF1R P08069 5/20 0.41
ALOX15 P16050 5/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
BACE1 P56817 1/20 0.40
ESR1 P03372 1/20 0.40
CYP19A1 P11511 1/20 0.40
ESR2 Q92731 1/20 0.40
KEAP1 Q14145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4289203 0.85 MAPT (0.53) MAPTMEN1KMT2AALOX5CA2
SCHEMBL4282537 0.80 MAPT (0.49) MAPTMEN1KMT2AALOX5CA2
SCHEMBL4287936 0.75 CYP4A11 (0.67) MAPTMEN1KMT2ACA2ALOX15
SCHEMBL11786007 0.75 TTR (0.47) BCHEACHEMAPTMEN1KMT2A
SCHEMBL4293661 0.75 ESR1 (0.49) MAPTMEN1KMT2AIGF1RALOX15
SCHEMBL4281392 0.75 SLC6A4 (0.45) MAPTMEN1KMT2AALOX5KEAP1
SCHEMBL2329516 0.74 CA2 (0.54) CA2ESR1ESR2
SCHEMBL29825054 0.73 BCHE (0.67) BCHEACHEMAPTMEN1KMT2A
SCHEMBL4283809 0.72 MAPT (0.53) BCHEACHEMAPTMEN1KMT2A
SCHEMBL4292350 0.72 SLC5A2 (0.48) MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 BCHE 2585/4885ACHE 3790/4885MAPT 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.