SCHEMBL4282537

SCHEMBL4282537

OCc1ccc(Cc2ccc(F)cc2)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ALOX5 P09917 2/20 0.47
DAO P14920 1/20 0.44
KEAP1 Q14145 1/20 0.41
HSP90AA1 P07900 1/20 0.40
TTR P02766 1/20 0.40
BCL2 P10415 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CNR2 P34972 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4289203 0.90 MAPT (0.53) MAPTMEN1KMT2AALOX5KEAP1
SCHEMBL4288684 0.80 BCHE (0.47) MAPTMEN1KMT2AALOX5KEAP1
SCHEMBL11786007 0.79 TTR (0.47) MAPTMEN1KMT2AALOX5TTR
SCHEMBL4281392 0.79 SLC6A4 (0.45) MAPTMEN1KMT2AALOX5KEAP1
SCHEMBL4293661 0.79 ESR1 (0.49) MAPTMEN1KMT2AHSP90AA1TTR
SCHEMBL4279587 0.79 SLC6A4 (0.47) MAPTMEN1KMT2AALOX5TTR
SCHEMBL4292350 0.76 SLC5A2 (0.48) MAPTMEN1KMT2ALMNA
SCHEMBL2577181 0.76 KEAP1 (0.70) MAPTMEN1KMT2AALOX5KEAP1
SCHEMBL6202888 0.76 MAPT (0.53) MAPTMEN1KMT2AALOX5KEAP1
SCHEMBL4288408 0.74 TUBB4A (0.47) MEN1KMT2ATTRCA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 MAPT 2884/4885MEN1 3776/4885KMT2A 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.