Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289405 | 1.00 | CPA1 (0.40) | CPA1ALDH1A1TDP1MEN1LMNA | |
| SCHEMBL11444664 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1LMNABLM | |
| SCHEMBL14658223 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1LMNABLM | |
| SCHEMBL4292493 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1LMNABLM | |
| SCHEMBL14659111 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1LMNATSHR | |
| SCHEMBL12341106 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1LMNATSHR | |
| SCHEMBL3328096 | 0.74 | — | — | |
| SCHEMBL3328089 | 0.74 | — | — | |
| SCHEMBL29021054 | 0.73 | KDM4E (0.36) | CPA1ALDH1A1TDP1LMNATSHR | |
| SCHEMBL265274 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637696-B2 | Methods for preparing amides and amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130030210-A1 | METHODS FOR PREPARING AMIDES AND AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-31 | — | — | US | disclosed |
| US-20090264676-A1 | Amino acids and catalytic preparatory methods | WARF - WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030210-A1 | METHODS FOR PREPARING AMIDES AND AMINO ACIDS | DNPEP, PTMS, QPCT | CPA1 1881/4885ALDH1A1 733/4885TDP1 3083/4885 |
| US-20090264676-A1 | Amino acids and catalytic preparatory methods | DNPEP, PREP, ENPEP | CPA1 1428/4885ALDH1A1 778/4885TDP1 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.