Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | MME | P08473 | 4/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289464 | 1.00 | ACE (0.54) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL29755521 | 0.85 | ACE (0.55) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL12344144 | 0.84 | ACE (0.54) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL6294116 | 0.82 | MMP2 (0.62) | ACEMMECPA1ACE2MMP2 | |
| SCHEMBL4242808 | 0.82 | MME (0.64) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL5966735 | 0.82 | MME (0.64) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL13609083 | 0.81 | MME (0.68) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL31214776 | 0.81 | GNPAT (0.60) | ACECTSSMMP9CTSLCTSB | |
| SCHEMBL31255864 | 0.81 | ACE (0.53) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL29269401 | 0.81 | ACE (0.74) | ACECTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637696-B2 | Methods for preparing amides and amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130030210-A1 | METHODS FOR PREPARING AMIDES AND AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-31 | — | — | US | disclosed |
| US-8269039-B2 | Amino acids and catalytic preparatory methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090264676-A1 | Amino acids and catalytic preparatory methods | WARF - WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030210-A1 | METHODS FOR PREPARING AMIDES AND AMINO ACIDS | DNPEP, PTMS, QPCT | ACE 313/4885MME 104/4885CPA1 1881/4885 |
| US-20090264676-A1 | Amino acids and catalytic preparatory methods | DNPEP, PREP, ENPEP | ACE 265/4885MME 129/4885CPA1 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.