Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | MC1R | Q01726 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289486 | 0.81 | HDAC4 (0.38) | HDAC4HDAC7HDAC5HDAC3HDAC1 | |
| SCHEMBL6944548 | 0.81 | CYP1A2 (0.44) | HDAC4HDAC7HDAC5HDAC3HDAC1 | |
| SCHEMBL540725 | 0.80 | MEN1 (0.43) | KDM1ASIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL16008920 | 0.80 | MEN1 (0.43) | KDM1ASIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL29831499 | 0.80 | MEN1 (0.43) | KDM1ASIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL4283038 | 0.80 | KDM1A (0.42) | KDM1ASIGMAR1HTR2AANPEP | |
| SCHEMBL4286040 | 0.80 | KDM1A (0.42) | KDM1ASIGMAR1HTR2AANPEP | |
| SCHEMBL16150008 | 0.80 | MEN1 (0.43) | KDM1ASIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL8269273 | 0.80 | MEN1 (0.43) | KDM1ASIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL29633476 | 0.80 | MEN1 (0.43) | KDM1ASIGMAR1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | disclosed |