⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL5069101 | 0.69 | GABRP (0.31) | — | |
| SCHEMBL4285379 | 0.69 | — | — | |
| SCHEMBL3844414 | 0.64 | GABRP (0.42) | — | |
| SCHEMBL9067075 | 0.61 | FDPS (0.44) | — | |
| SCHEMBL5271897 | 0.61 | GABRP (0.39) | — | |
| SCHEMBL4734633 | 0.59 | GABRP (0.38) | — | |
| SCHEMBL4629162 | 0.59 | GABRP (0.38) | — | |
| SCHEMBL28066179 | 0.59 | GABRP (0.31) | — | |
| SCHEMBL642294 | 0.59 | TDP1 (0.41) | — | |
| SCHEMBL647581 | 0.59 | TDP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829040-B2 | (aza)indole derivative and use thereof for medical purposes | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20140179932-A1 | (AZA)INDOLE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8658668-B2 | PI3 kinase/mTOR dual inhibitor | ELI LILLY AND COMPANY (US) | 2014-02-25 | — | — | US | disclosed |
| US-20090203108-A1 | Method for preparing maltogenic alpha-amylase variants | NOVOZYMES A/S (DK) | 2009-08-13 | — | — | US | disclosed |
| US-6753462-B2 | Transgenic plants with increased calcium stores | NORTH CAROLINA STATE UNIVERSITY | 2004-06-22 | — | — | US | disclosed |
| US-20020083496-A1 | Transgenic plants with increased calcium stores | NORTH CAROLINA STATE UNIVERSITY | 2002-06-27 | — | — | US | disclosed |
| WO-2001083789-A2 | TRANSGENIC PLANTS WITH INCREASED CALCIUM STORES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-11-08 | — | — | WO | disclosed |
| EP-0128706-A2 | Body implants of extracellular matrix and means and methods of making and using such implants | UNIVERSITY PATENTS, INC. (US) | 1984-12-19 | — | — | EP | disclosed |