SCHEMBL429163

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4126197	0.86	KDR (0.57)	KDM4EALDH1A1HIF1AMAPTTP53
	SCHEMBL4270423	0.84	EGFR (0.53)	KDM4EALDH1A1HIF1AMAPTTP53
	SCHEMBL430392	0.79	KDR (0.56)	KDM4EALDH1A1HIF1AMTOREGFR
	SCHEMBL4121881	0.79	BRAF (0.67)	EGFRBRAFKDR
	SCHEMBL4113865	0.72	TP53 (0.59)	MAPTTP53POLBPIK3CASRC
	SCHEMBL14586502	0.72	TSHR (0.56)	KDM4EALDH1A1HIF1AMAPTPIK3CA
	SCHEMBL4105902	0.71	ALDH1A1 (0.64)	KDM4EALDH1A1MAPTTP53HTT
	SCHEMBL423982	0.69	ALDH1A1 (0.57)	KDM4EALDH1A1HIF1AMAPTTP53
	SCHEMBL426756	0.69	BRAF (0.56)	EGFRBRAFKDR
	SCHEMBL424206	0.69	BRAF (0.55)	EGFRBRAFKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.