Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 3/20 | 0.65 |
| ▸ | CMA1 | P23946 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664274 | 1.00 | CTSG (0.65) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL6942656 | 1.00 | CTSG (0.65) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL14363442 | 0.87 | CTSG (0.62) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL14865867 | 0.87 | CTSG (0.62) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL13536304 | 0.87 | CTSG (0.62) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL7148922 | 0.85 | ACE (0.64) | CTSGCMA1L3MBTL1ACE | |
| SCHEMBL6496041 | 0.85 | ACE (0.64) | CTSGCMA1L3MBTL1ACE | |
| SCHEMBL7499927 | 0.84 | CTSG (0.59) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL4976559 | 0.84 | CTSG (0.59) | CTSGCMA1ALDH1A1HTTNCOA1 | |
| SCHEMBL7486728 | 0.84 | CTSG (0.59) | CTSGCMA1ALDH1A1HTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | claimed |
| US-6150567-A | REACTING CARBONYL COMPOUND WITH ORGANOALUMINUM COMPOUND TO FORM AN ALCOHOL COMPOUND | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | claimed |
| EP-0963972-A2 | Stereoselective reduction of carbonyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-15 | — | — | EP | claimed |
| EP-0827943-A1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORPORATION (JP) | 1998-03-11 | — | — | EP | claimed |
| EP-2807145-B1 | A METHOD FOR THE PREPARATION OF DIAZOALKANES | BAKHU LTD (GB) | 2017-03-22 | — | — | EP | disclosed |
| US-9593073-B2 | Method for the preparation of diazoalkanes | BAKHU LIMITED (GB) | 2017-03-14 | — | — | US | disclosed |
| US-20150038687-A1 | METHOD FOR THE PREPARATION OF DIAZOALKANES | BAKHU LIMITED (GB) | 2015-02-05 | — | — | US | disclosed |
| EP-1309714-B1 | STEREOSELECTIVE REDUCTION OF SUBSTITUTED OXO-BUTANES | BRISTOL MYERS SQUIBB CO (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6150567-A | REACTING CARBONYL COMPOUND WITH ORGANOALUMINUM COMPOUND TO FORM AN ALCOHOL COMPOUND | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| US-H1893-H | REACTING A HALOKETONE COMPOUND OR SALT WITH AN OXIDOREDUCTASE ENZYME SUPPLYING MICROORGANISM OR OXIDOREDUCTASE ENZYME CONTAINING MATERIAL OBTAINED FROM THE MICROORGANISM, CATALYZES THE REDUCTION OF HALOKETONE TO FORM HALOHYDROXIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0963972-A2 | Stereoselective reduction of carbonyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-15 | — | — | EP | disclosed |
| EP-0154904-A1 | Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines | E.R. Squibb & Sons, Inc. (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4535176-A | HYPOTENSIVE AGENTS, ANALGESICS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0142335-A2 | Lactam containing compounds | E.R. Squibb & Sons, Inc. (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4514391-A | HYPOTENSIVE AGENTS; ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1985-04-30 | — | — | US | disclosed |
| US-4512988-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-04-23 | — | — | US | disclosed |
| EP-0132304-A2 | Hydroxy substituted peptide compounds | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4474778-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4470973-A | HYPOTENSIVE AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1984-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038687-A1 | METHOD FOR THE PREPARATION OF DIAZOALKANES | NIT2, DNTT, NAT1 | CTSG 3762/4885CMA1 1708/4885ALDH1A1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.