Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 3/20 | 0.62 |
| ▸ | CMA1 | P23946 | 3/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 1/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363442 | 1.00 | CTSG (0.62) | CTSGCMA1CTSSCTSKPAM | |
| SCHEMBL13857697 | 0.89 | CTSG (0.54) | CTSGCMA1CTSSCTSKPAM | |
| SCHEMBL6942656 | 0.87 | CTSG (0.65) | CTSGCMA1ACEALDH1A1HTT | |
| SCHEMBL4291672 | 0.87 | CTSG (0.65) | CTSGCMA1ACEALDH1A1HTT | |
| SCHEMBL5664274 | 0.87 | CTSG (0.65) | CTSGCMA1ACEALDH1A1HTT | |
| SCHEMBL20079849 | 0.85 | CTSS (0.60) | CTSSCTSKPAMCTRB1TACR1 | |
| SCHEMBL14865877 | 0.85 | CTSS (0.60) | CTSSCTSKPAMCTRB1TACR1 | |
| SCHEMBL7499927 | 0.84 | CTSG (0.59) | CTSGCMA1CTSSCTSKACE | |
| SCHEMBL7486728 | 0.84 | CTSG (0.59) | CTSGCMA1CTSSCTSKACE | |
| SCHEMBL4976559 | 0.84 | CTSG (0.59) | CTSGCMA1CTSSCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096317-A1 | REDUCTION OF ALDEHYDES AND KETONES TO ALCOHOLS | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096317-A1 | REDUCTION OF ALDEHYDES AND KETONES TO ALCOHOLS | POF1B, PHF2, ADH1C | CTSG 4804/4885CMA1 1440/4885CTSS 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.