SCHEMBL4292104

SCHEMBL4292104

CCCCCCCCCCCCCCCc1ccc(C(=O)c2ccccc2OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 4/20 0.55
PPARG P37231 1/20 0.54
PPARA Q07869 1/20 0.54
PLK3 Q9H4B4 3/20 0.52
RARB P10826 4/20 0.50
THRA P10827 2/20 0.50
THRB P10828 2/20 0.50
SMPD1 P17405 1/20 0.50
STS P08842 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
RARA P10276 1/20 0.50
MAPT P10636 1/20 0.50
MTOR P42345 1/20 0.50
KMT2A Q03164 1/20 0.50
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597931 0.84 PPARA (0.62) PLK1PPARGPPARASMPD1MAPT
SCHEMBL4292099 0.84 PPARA (0.74) PLK1PPARGPPARAMAPT
SCHEMBL19757441 0.84 HDAC8 (0.54) STSCNR1CNR2NPC1RAB9A
SCHEMBL5422705 0.83 PLK1 (0.56) PLK1PLK3RARBTHRATHRB
SCHEMBL918747 0.82 PLK1 (0.66) PLK1PPARAPLK3RARBTHRA
SCHEMBL4285675 0.82 PLK1 (0.58) PLK1PLK3RARBTHRATHRB
SCHEMBL11863439 0.82 PLK1 (0.58) PLK1PLK3RARBTHRATHRB
SCHEMBL11526984 0.81 PLK1 (0.54) PLK1PLK3RARBTHRATHRB
SCHEMBL4354691 0.81 THRA (0.56) PLK1PLK3RARBTHRATHRB
SCHEMBL5414509 0.81 PLK1 (0.54) PLK1PLK3RARBTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090068126-A1 Composition for surface photoprotection SOARES ROMEIRO LUIZ ANTONIO 2009-03-12 US disclosed
EP-1812027-A2 COMPOUNDS CAPABLE OF ABSORBING ULTRAVIOLET RADIATION, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION Universidade Federal Do Rio De Janeiro - UFRJ (BR) 2007-08-01 EP disclosed
WO-2006042391-A2 PHOTOPROTECTIVE PHENOL DERIVATIVES OBTAINED FROM CASHEW NUT-SHELL LIQUID UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) 2006-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068126-A1 Composition for surface photoprotection S100A10, CD63, S100A9 PLK1 2263/4885PPARG 2023/4885PPARA 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.