SCHEMBL4292685

SCHEMBL4292685

Oc1ccc(Cl)c(-c2ccccc2)c1Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ESR2 Q92731 3/20 0.42
IDH1 O75874 1/20 0.42
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40
ACMSD Q8TDX5 1/20 0.39
ESR1 P03372 2/20 0.39
POLB P06746 1/20 0.38
ABCB1 P08183 2/20 0.37
CALM1 P0DP23 1/20 0.37
HNF4A P41235 1/20 0.37
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4286155 0.86 MEN1 (0.45) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL9790331 0.82 MEN1 (0.50) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL5178275 0.80 MEN1 (0.49) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL30821519 0.80 MEN1 (0.49) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL7582785 0.80 MEN1 (0.49) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL560333 0.77 MEN1 (0.46) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL27886772 0.77 MEN1 (0.46) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL27657488 0.77 IDH1 (0.58) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL6428533 0.77 BCL2L1 (0.44) HPGDHSD17B10IDH1HTTLMNA
SCHEMBL27588764 0.75 ESR2 (0.52) MEN1KMT2ACYP3A4HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US claimed
WO-2009120784-A2 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2009-10-01 WO claimed
US-6022549-A NONAQUEOUS, COMPRISING A PHENOL ANTIMICROBIAL AGENT, A FILM FORMING RESIN, AND ORGANIC SOLVENT; THE PHENOL IS STORAGE STABLE AND CAPABLE OF LEACHING FOLLOWING SOLIDIFICATION OF THE NAIL COATING WITHOUT LOSING MICROBIOCIDAL ACTIVITY WOODWARD LABORATORIES, INC. (US) 2000-02-08 US claimed
WO-1999036033-A1 ANTIMICROBIAL NAIL COATING COMPOSITION WOODWARD LABORATORIES, INC. (US) 1999-07-22 WO claimed
US-20190257049-A1 Methods and Apparatus for Stabilization of Surfaces Polylast Systems, LLC 2019-08-22 US disclosed
US-10309070-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2019-06-04 US disclosed
US-9982143-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2018-05-29 US disclosed
US-20170002533-A1 Methods and Apparatus for Stabilization of Surfaces KING COAST INC. 2017-01-05 US disclosed
US-20160333192-A1 Methods and Apparatus for Stabilization of Surfaces KING COAST INC. 2016-11-17 US disclosed
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US disclosed
US-7244418-B2 Antimicrobial artificial nail composition and methods for preparing and using same WOODWARD LABORATORIES, INC. (US) 2007-07-17 US disclosed
US-20030086880-A1 Antimicrobial artificial nail composition and methods for preparing and using same BROWN RUDNICK LLP 2003-05-08 US disclosed
US-6479039-B1 Antimicrobial artificial nail composition and methods for preparing and using same WOODWARD LABORATORIES, INC. 2002-11-12 US disclosed
US-20020165260-A1 Compositions and methods for the treatment and prevention of bovine mastitis BROWN RUDNICK LLP 2002-11-07 US disclosed
WO-2002069954-A1 COMPOSITION AND METHODS FOR THE TREATMENT AND PREVENTION OF BOVINE MASTITIS MCJ, INC. (US) 2002-09-12 WO disclosed
WO-2001003656-A1 ANTIMICROBIAL ARTIFICIAL NAIL COMPOSITION AND METHODS FOR PREPARING AND USING SAME WOODWARD LABORATORIES, INC. (US) 2001-01-18 WO disclosed
US-6022549-A NONAQUEOUS, COMPRISING A PHENOL ANTIMICROBIAL AGENT, A FILM FORMING RESIN, AND ORGANIC SOLVENT; THE PHENOL IS STORAGE STABLE AND CAPABLE OF LEACHING FOLLOWING SOLIDIFICATION OF THE NAIL COATING WITHOUT LOSING MICROBIOCIDAL ACTIVITY WOODWARD LABORATORIES, INC. (US) 2000-02-08 US disclosed
US-6013677-A APPLYING TO THE NAIL A NON-AQUEOUS ANTIMICROBIAL NAIL COATING CONTAINING A FILM FORMING POLYMER, AN ORGANIC SOLVENT, A ANTIMICROBIAL AGENT COMPRISING SOLUBILZED BENZALKONIUM CHLORIDE AND CAPABLE OF LEACHING FROM NAIL COATING WOODWARD LABORATORIES, INC. (US) 2000-01-11 US disclosed
US-5968986-A NONAQUEOUS NAIL COATING WITH MICROBIOCDES AND POLYMERS WOODWARD LABORATORIES, INC. (US) 1999-10-19 US disclosed
WO-1999036033-A1 ANTIMICROBIAL NAIL COATING COMPOSITION WOODWARD LABORATORIES, INC. (US) 1999-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030086880-A1 Antimicrobial artificial nail composition and methods for preparing and using same POLR1C, NACA, PIK3C3 MEN1 482/4885KMT2A 2475/4885CYP3A4 4046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.