Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578395 | 1.00 | CTSD (0.45) | CTSDBACE1IRAK4DDB1CRBN | |
| SCHEMBL2790837 | 0.86 | MEN1 (0.45) | CTSDBACE1DDB1CRBNALDH1A1 | |
| SCHEMBL2790835 | 0.86 | MEN1 (0.45) | CTSDBACE1DDB1CRBNALDH1A1 | |
| SCHEMBL24687316 | 0.84 | MMP13 (0.43) | MMP13TDP1ALDH1A1 | |
| SCHEMBL29200821 | 0.84 | MMP13 (0.43) | MMP13TDP1ALDH1A1 | |
| SCHEMBL29200819 | 0.84 | MMP13 (0.43) | MMP13TDP1ALDH1A1 | |
| SCHEMBL4293099 | 0.84 | DDB1 (0.46) | CTSDBACE1DDB1CRBNMMP13 | |
| SCHEMBL4293100 | 0.84 | DDB1 (0.46) | CTSDBACE1DDB1CRBNMMP13 | |
| SCHEMBL7451040 | 0.84 | DDB1 (0.46) | CTSDBACE1DDB1CRBNMMP13 | |
| SCHEMBL2034179 | 0.82 | HPGD (0.47) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |