Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 8/20 | 0.58 |
| ▸ | MMP1 | P03956 | 5/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293140 | 1.00 | MMP13 (0.58) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL11197364 | 0.81 | MMP13 (0.53) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL7672124 | 0.80 | MMP13 (0.77) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL6691597 | 0.80 | MMP13 (0.77) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL13986105 | 0.75 | HPGD (0.46) | MMP13POLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6698104 | 0.75 | MMP13 (1.00) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL11193620 | 0.74 | MMP13 (0.38) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL10341454 | 0.73 | KMT2A (0.49) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL31581689 | 0.73 | S1PR5 (0.59) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL20701414 | 0.72 | NPC1 (0.51) | MMP13CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62022797-A | — | — | None | — | — | JP | disclosed |
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |
| JP-S6222797-A | NOVEL PEPTIDE AND PRODUCTION THEREOF | TANABE SEIYAKU CO LTD | 1987-01-30 | — | — | JP | disclosed |
| US-4508727-A | Antihypertensive 2-oxo-imidazolidine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |
| US-4380644-A | HYPOTENSIVE AGENTS | TANABE SIYAKU CO., LTD. (JP) | 1983-04-19 | — | — | US | disclosed |
| EP-0052696-A1 | Novel 2-oxoimidazolidine derivative, a process for preparing same and a pharmaceutical composition containing the 2-oxoimidazolidine derivative | Tanabe Seiyaku Co., Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |