Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455943 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL29418178 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL6152165 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL31439257 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL31633515 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL31633516 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL6151660 | 0.67 | CYP3A4 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL11066558 | 0.67 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL4293163 | 0.67 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL188682 | 0.65 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009114133-A1 | CELLS AND ASSAYS FOR USE IN DETECTING LONG QT SYNDROME | THE J. DAVID GLADSTONE INSTITUTES (US) | 2009-09-17 | — | — | WO | disclosed |
| US-20090227469-A1 | CELLS AND ASSAYS FOR USE IN DETECTING LONG QT SYNDROME | THE J. DAVID GLADSTONE INSTITUTES | 2009-09-10 | — | — | US | disclosed |