⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43137 | 0.95 | PTPN1 (0.32) | — | |
| SCHEMBL677783 | 0.93 | CYP11B2 (0.34) | — | |
| SCHEMBL25216 | 0.93 | CYP11B2 (0.34) | — | |
| SCHEMBL2911923 | 0.93 | CYP11B2 (0.34) | — | |
| SCHEMBL7838054 | 0.93 | CYP11B2 (0.34) | — | |
| SCHEMBL24524 | 0.91 | — | — | |
| SCHEMBL7763956 | 0.83 | — | — | |
| SCHEMBL694970 | 0.83 | SLC18A3 (0.44) | — | |
| SCHEMBL17090722 | 0.83 | — | — | |
| SCHEMBL2761445 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731954-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RES INC (US) | 2023-08-22 | — | — | US | claimed |
| US-20210238161-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2021-08-05 | — | — | US | claimed |
| US-11001568-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2021-05-11 | — | — | US | claimed |
| US-20200157077-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-05-21 | — | — | US | claimed |
| CN-110372756-A | Bivalent platinum complex and preparation method and application thereof | 南京工业大学 | 2019-10-25 | — | — | CN | claimed |
| CN-109748938-A | Bivalent platinum complex, application thereof and organic photoelectric device | 南京工业大学 | 2019-05-14 | — | — | CN | claimed |
| CN-106459043-B | Naphthyridines derovatives | 诺华股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| EP-3397617-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2018-11-07 | — | — | EP | claimed |
| CN-108698997-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2018-10-23 | — | — | CN | claimed |
| US-10059687-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-08-28 | — | — | US | claimed |
| EP-2035420-A2 | KV1.5 POTASSIUM CHANNEL INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2008098244-A1 | NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR | METABASIS THERAPEUTICS, INC. (US) | 2008-08-14 | — | — | WO | claimed |
| CN-101212974-A | 4-fluoro-piperidine T-type calcium channel antagonists | MERCK & CO INC (US) | 2008-07-02 | — | — | CN | claimed |
| EP-1901746-A2 | 4-FLUORO-PIPERIDINE T-TYPE CALCIUM CHANNEL ANTAGONISTS | Merck & Co., Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| EP-1896414-A2 | 3-FLUORO-PIPERIDINE T-TYPE CALCIUM CHANNEL ANTAGONISTS | Merck & Co., Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| CN-101115731-A | Oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-01-30 | — | — | CN | claimed |
| WO-2007149873-A2 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | WO | claimed |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | claimed |
| WO-2007002884-A2 | 4-FLUORO-PIPERIDINE T-TYPE CALCIUM CHANNEL ANTAGONISTS | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | claimed |
| WO-2007002361-A2 | 3-FLUORO-PIPERIDINE T-TYPE CALCIUM CHANNEL ANTAGONISTS | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | claimed |