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Dideoxy Guanosine Triphosphate

Dideoxy Guanosine Triphosphate

SCHEMBL4293277

Nc1nc2c(ncn2[C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1.Nc1ncnc2c1ncn2[C@H]1CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1.O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C[C@@H]1O

nearest known ligand 0.61

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.61
▸ P2RY2 P41231 3/20 0.58
▸ P2RY4 P51582 1/20 0.58
▸ P2RY6 Q15077 1/20 0.58
▸ DTYMK P23919 4/20 0.57
▸ P2RY1 P47900 4/20 0.52
▸ ENPP1 P22413 3/20 0.52
▸ P2RX1 P51575 2/20 0.50
▸ P2RX3 P56373 2/20 0.50
▸ P2RX2 Q9UBL9 2/20 0.50
▸ TERT O14746 1/20 0.48
▸ SRC P12931 1/20 0.48
▸ P2RX4 Q99571 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyguanosine Triphosphate SCHEMBL5055758 0.91 POLB (0.72) POLBP2RY2P2RY4P2RY6DTYMK
Dideoxy Guanosine Triphosphate SCHEMBL6915085 0.91 POLB (0.54) POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL24219865 0.87 POLB (0.71) POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL16699229 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK
Deoxyguanosine Triphosphate SCHEMBL80609 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK
Deoxyguanosine Triphosphate SCHEMBL18785123 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK
Deoxyguanosine Triphosphate SCHEMBL12729493 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK
Deoxyguanosine Triphosphate SCHEMBL2820367 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL3042901 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK
Deoxyguanosine Triphosphate SCHEMBL252797 0.85 POLB (0.81) POLBP2RY2P2RY4P2RY6DTYMK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8314209-B2 Lipid-assisted synthesis of polymer compounds and methods for their use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-20 — — US disclosed
US-20090264621-A1 Lipid-assisted synthesis of polymer compounds and methods for their use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-10-22 — — US disclosed
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