SCHEMBL429333

SCHEMBL429333

CCCCCCCCCCCC(CCCCCCCC)OCCO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HTT P42858 2/20 0.48
MAPT P10636 2/20 0.48
THRB P10828 1/20 0.48
LMNA P02545 4/20 0.46
DNM1 Q05193 1/20 0.45
TSHR P16473 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 1/20 0.44
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CYP2D6 P10635 2/20 0.39
SPHK1 Q9NYA1 1/20 0.39
GMNN O75496 1/20 0.39
POLB P06746 1/20 0.39
THPO P40225 1/20 0.39
MTOR P42345 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977019 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL30977011 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL30977034 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL8642161 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL490564 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL16175782 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL30977017 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL8772499 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL30977015 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB
SCHEMBL30977024 1.00 MEN1 (0.48) MEN1KMT2AHTTMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190321329-A1 FORMULATION FOR THE TREATMENT OF ACNE AKZO NOBEL CHEMICALS INT BV (NL) 2019-10-24 US disclosed
EP-3340975-B1 FORMULATION FOR THE TREATMENT OF ACNE AKZO NOBEL CHEMICALS INT BV (NL) 2019-07-24 EP disclosed
US-10278945-B2 Formulation for the treatment of acne AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2019-05-07 US disclosed
US-20190022050-A1 FORMULATION FOR THE TREATMENT OF ACNE NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2019-01-24 US disclosed
EP-3340975-A1 FORMULATION FOR THE TREATMENT OF ACNE Akzo Nobel Chemicals International B.V. (NL) 2018-07-04 EP disclosed
US-20170156999-A1 PERSONAL CARE COMPOSITION IN A DISSOLVABLE CONTAINER Henkel IP & Holding GmbH (DE) 2017-06-08 US disclosed
WO-2017036897-A1 FORMULATION FOR THE TREATMENT OF ACNE AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2017-03-09 WO disclosed
EP-2393469-B1 Process of treating hair RHODIA OPERATIONS (FR) 2016-10-12 EP disclosed
EP-2419077-B1 PROCESS OF TREATING DAMAGED HAIR RHODIA OPERATIONS (FR) 2016-10-12 EP disclosed
US-9072675-B2 Non-irritating benzoyl peroxide ESSENTIAL INGREDIENTS, INC. (US) 2015-07-07 US disclosed
EP-1663117-A1 COSMETIC COMPOSITIONS IN SINGLE PORTION PACKAGINGS Henkel Kommanditgesellschaft auf Aktien (DE) 2006-06-07 EP disclosed
WO-2006018328-A2 COMPACT HAIRSPRAY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-02-23 WO disclosed
WO-2005060924-A1 COSMETIC AGENTS PROVIDING VOLUME HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-07-07 WO disclosed
WO-2005060926-A1 SPRAYABLE GEL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-07-07 WO disclosed
WO-2004100901-A2 COSMETIC COMPOSITIONS IN SINGLE PORTION PACKAGINGS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-11-25 WO disclosed
EP-1408912-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS Dow Corning Corporation (US) 2004-04-21 EP disclosed
US-6645502-B2 Pigmented composition for reducing shiny appearance of skin and cosmetically improving appearance of skin imperfections REVLON CONSUMER PRODUCTS CORPORATION 2003-11-11 US disclosed
WO-2003009819-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS DOW CORNING CORPORATION (US) 2003-02-06 WO disclosed
US-6498197-B1 Temperature insensitive one-phase microemulsions DOW CORNING CORPORATION 2002-12-24 US disclosed
US-6485731-B2 CONDITIONING NAILS OR SURROUNDING CUTICLE WITH A COMPOSITION THAT HAS < 5% OF A FLUORINATED SILICONE OIL REVLON CONSUMER PRODUCTS CORPORATION 2002-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190321329-A1 FORMULATION FOR THE TREATMENT OF ACNE ACOX1, HSD17B12, ACOX3 MEN1 3621/4885KMT2A 3955/4885HTT 3288/4885
US-20190022050-A1 FORMULATION FOR THE TREATMENT OF ACNE ACOX1, HSD17B12, ACOX3 MEN1 3621/4885KMT2A 3955/4885HTT 3288/4885
US-10278945-B2 Formulation for the treatment of acne ACOX1, HSD17B12, ACOX3 MEN1 3621/4885KMT2A 3955/4885HTT 3288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.