SCHEMBL429352

SCHEMBL429352

CCCCCCc1ccc2c(c1)sc1c3ccccc3sc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.43
RORA P35398 1/20 0.43
RORC P51449 1/20 0.43
RORB Q92753 1/20 0.43
SLC6A2 P23975 3/20 0.41
SLC6A4 P31645 3/20 0.41
HTR2A P28223 3/20 0.41
HTR2C P28335 2/20 0.41
DRD2 P14416 1/20 0.41
CTSV O60911 1/20 0.40
CTSL P07711 1/20 0.40
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40
ADORA3 P0DMS8 2/20 0.40
TACR2 P21452 2/20 0.40
SLC6A3 Q01959 2/20 0.40
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9951172 1.00 GPR3 (0.43) GPR3RORARORCRORBSLC6A2
SCHEMBL10072886 1.00 GPR3 (0.43) GPR3RORARORCRORBSLC6A2
SCHEMBL17040006 1.00 GPR3 (0.43) GPR3RORARORCRORBSLC6A2
SCHEMBL17461410 1.00 GPR3 (0.43) GPR3RORARORCRORBSLC6A2
SCHEMBL15581058 1.00 GPR3 (0.43) GPR3RORARORCRORBSLC6A2
SCHEMBL708808 0.92 PTGS2 (0.46) GPR3SLC6A2SLC6A4HTR2AHTR2C
SCHEMBL30423034 0.92 PTGS2 (0.46) GPR3SLC6A2SLC6A4HTR2AHTR2C
SCHEMBL709940 0.92 PTGS2 (0.46) GPR3SLC6A2SLC6A4HTR2AHTR2C
SCHEMBL10031386 0.92 PTGS2 (0.46) GPR3SLC6A2SLC6A4HTR2AHTR2C
SCHEMBL31318821 0.92 PTGS2 (0.46) GPR3SLC6A2SLC6A4HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130146858-A1 SEMICONDUCTORS BASED ON SUBSTITUTED [1]BENZOTHIENO[3,2-b][1]-BENZOTHIOPHENES Heraeuss Precious Metals Metals GmbH & Co., KG (DE) 2013-06-13 US disclosed
US-20130146858-A1 SEMICONDUCTORS BASED ON SUBSTITUTED [1]BENZOTHIENO[3,2-b][1]-BENZOTHIOPHENES Heraeuss Precious Metals Metals GmbH & Co., KG (DE) 2013-06-13 US disclosed
EP-2595992-A1 SEMICONDUCTORS BASED ON SUBSTITUTED [1]BENZOTHIENO[3,2-b][1]-BENZOTHIOPHENES Heraeus Precious Metals GmbH & Co. KG (DE) 2013-05-29 EP disclosed
WO-2012010292-A1 SEMICONDUCTORS BASED ON SUBSTITUTED [1]BENZOTHIENO[3,2-b] [1]-BENZOTHIOPHENES HERAEUS CLEVIOS GMBH (DE) 2012-01-26 WO disclosed
WO-2012010292-A1 SEMICONDUCTORS BASED ON SUBSTITUTED [1]BENZOTHIENO[3,2-b] [1]-BENZOTHIOPHENES HERAEUS CLEVIOS GMBH (DE) 2012-01-26 WO disclosed