SCHEMBL4293788

SCHEMBL4293788

C[N+](CCO)(CCO)CC(COC(=O)CCCCCCCCCCC(=O)OCc1ccccc1)OC(=O)CCCCCCCCCCC(=O)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.43
PRKCE Q02156 2/20 0.43
PRKCQ Q04759 2/20 0.43
PRKCD Q05655 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
TLR2 O60603 4/20 0.43
MGLL Q99685 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
FABP3 P05413 1/20 0.41
LPAR1 Q92633 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13702213 0.88 ALDH1A1 (0.43) PRKCAPRKCDALDH1A1MAPK1L3MBTL1
SCHEMBL4078739 0.88 MAPK1 (0.48) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL13901188 0.84 CYP1A2 (0.44) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL13702237 0.83 L3MBTL1 (0.37) PRKCAPRKCDALDH1A1TLR2MAPK1
SCHEMBL4255720 0.82 ALDH1A1 (0.54) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL14216668 0.81 ALDH1A1 (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL18759378 0.81 ALDH1A1 (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1
Hydrochloric Acid SCHEMBL6839365 0.80 ALDH1A1 (0.65) PRKCAPRKCEPRKCQPRKCDALDH1A1
Iodide SCHEMBL1685005 0.80 ALDH1A1 (0.65) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL19300948 0.79 ALDH1A1 (0.68) PRKCAPRKCEPRKCQPRKCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221684-A1 Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof TRUSTEES OF BOSTON UNIVERSITY (US) 2009-09-03 US disclosed
WO-2007073489-A2 MOLECULES FOR GENE DELIVERY AND GENE THERAPY, AND METHODS OF USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221684-A1 Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof ANXA6, STING1, ADM2 PRKCA 3834/4885PRKCE 3795/4885PRKCQ 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.