SCHEMBL429412

SCHEMBL429412

CCOC(=O)c1ccc(C(=N)N)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP3A4 P08684 1/20 0.67
MAOA P21397 1/20 0.67
CA1 P00915 3/20 0.63
CA2 P00918 3/20 0.63
CA12 O43570 2/20 0.63
CA7 P43166 2/20 0.63
CA9 Q16790 2/20 0.63
CA14 Q9ULX7 2/20 0.63
ESR1 P03372 1/20 0.63
ESR2 Q92731 1/20 0.63
PRSS1 P07477 2/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
STS P08842 1/20 0.56
HPGD P15428 4/20 0.54
HTT P42858 2/20 0.54
NOS3 P29474 2/20 0.54
NOS1 P29475 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5548938 0.98 LMNA (0.65) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL87450 0.85 CA1 (0.83) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL6896360 0.84 LMNA (0.71) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL5541652 0.84 NPC1 (0.54) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL5543055 0.84 NPC1 (0.54) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL7746905 0.83 CA1 (0.79) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL30271267 0.83 CA1 (0.79) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL21440358 0.83 CA1 (0.79) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL29504635 0.83 CA1 (0.79) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL27667923 0.83 CA1 (0.79) LMNACYP1A2CYP3A4MAOACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480451-A Amidine ultraviolet absorbent, preparation method and application thereof 天津利安隆新材料股份有限公司 2021-10-08 CN claimed
CN-103709073-B Preparation method of N,N'-bis (4-ethoxycarbonylphenyl)-N'-benzyl formamidine CHANGZHOU YONGHE FINE CHEMICAL CO LTD 2015-07-22 CN claimed
US-5823180-A PHOSPHODIESTERASE INHIBITOR AND INHALING NITRIC OXIDE THE GENERAL HOSPITAL CORPORATION (US) 1998-10-20 US claimed
CN-112047859-B Method for preparing N, N '-di (4-ethoxycarbonylphenyl) -N' -benzyl formamidine from waste residues generated in production of UV-1 常州永和精细化学有限公司 2023-11-03 CN disclosed
CN-113480451-A Amidine ultraviolet absorbent, preparation method and application thereof 天津利安隆新材料股份有限公司 2021-10-08 CN disclosed
CN-112047859-A Method for preparing N, N '-di (4-ethoxycarbonylphenyl) -N' -benzylformamidine from waste residues generated in UV-1 production 常州永和精细化学有限公司 2020-12-08 CN disclosed
CN-105315176-B Green preparation process of N- (4-ethoxycarbonylphenyl) -N '-methyl-N' -phenylformamidine 常州永和精细化学有限公司 2020-03-31 CN disclosed
CN-105315176-A Environment-friendly preparation process of N-(4-ethoxy carbonyl phenyl)-N'-methyl-N'-phenyl formamidine CHANGZHOU YONGHE FINE CHEMICAL CO LTD 2016-02-10 CN disclosed
CN-103709073-B Preparation method of N,N'-bis (4-ethoxycarbonylphenyl)-N'-benzyl formamidine CHANGZHOU YONGHE FINE CHEMICAL CO LTD 2015-07-22 CN disclosed
CN-103709073-B Preparation method of N,N'-bis (4-ethoxycarbonylphenyl)-N'-benzyl formamidine CHANGZHOU YONGHE FINE CHEMICAL CO LTD 2015-07-22 CN disclosed
CN-103709073-A Preparation method of N,N'-bis (4-ethoxycarbonylphenyl)-N'-benzyl formamidine CHANGZHOU YONGHE FINE CHEMICAL CO LTD 2014-04-09 CN disclosed
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
US-5650424-A ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES DR. KARL THOMAE GMBH (DE) 1997-07-22 US disclosed
US-5478942-A Antiinflammatory agents, antiagglomerants KARL THOMAE GMBH (DE) 1995-12-26 US disclosed
US-5276049-A Treatment of thrombosis DR. KARL THOMAE GMBH (DE) 1994-01-04 US disclosed
US-4180475-A POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-12-25 US disclosed
US-4066570-A OPTICAL CELLS, NEMATIC MIXTURES, LIQUID CRYSTALS HOFFMAN-LA ROCHE INC. (US) 1978-01-03 US disclosed
US-4062798-A NEMATIC CRYSTALS HOFFMANN-LA ROCHE INC. (US) 1977-12-13 US disclosed
US-3997536-A LIQUID CRYSTALS HOFFMANN-LA ROCHE INC. (US) 1976-12-14 US disclosed