Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651111 | 0.85 | PNMT (0.60) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL28771460 | 0.83 | PNMT (0.58) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL29091904 | 0.83 | PNMT (0.58) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL28771456 | 0.83 | PNMT (0.58) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL8153800 | 0.83 | PNMT (0.69) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL2427261 | 0.83 | PNMT (0.69) | PNMTTSHRRECQLTAAR1HTR3E | |
| Hydrochloric Acid SCHEMBL7864518 | 0.82 | PNMT (0.67) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL30615772 | 0.82 | PNMT (0.56) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL1552426 | 0.82 | PNMT (0.56) | PNMTTSHRRECQLTAAR1HTR3E | |
| SCHEMBL25518189 | 0.82 | PNMT (0.56) | PNMTTSHRRECQLTAAR1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275077-A1 | Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides | OXYRANE (UK) LIMITED (GB) | 2009-11-05 | — | — | US | disclosed |
| US-20070281339-A1 | Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides | OXYRANE UK LIMITED (GB) | 2007-12-06 | — | — | US | disclosed |
| EP-1756281-A2 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM STYRENE EPOXIDES USING ENANTIOSELECTIVE EPOXIDE HYDROLASES DERIVED FROM YEASTS | CSIR (ZA) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100569-A2 | METHODS FOR THE PREPARATION OF OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM STYRENE EPOXIDES USING ENANTIOSELECTIVE EPOXIDE HYDROLASES DERIVED FROM YEASTS | CSIR (ZA) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275077-A1 | Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides | EPHX2, EPHX1, DERA | PNMT 416/4885TSHR 4879/4885RECQL 556/4885 |
| US-20070281339-A1 | Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides | DERA, ERG28, EPHX2 | PNMT 982/4885TSHR 4867/4885RECQL 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.