Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | CCR1 | P32246 | 3/20 | 0.67 |
| ▸ | CCR5 | P51681 | 3/20 | 0.67 |
| ▸ | CCR8 | P51685 | 3/20 | 0.67 |
| ▸ | METAP1 | P53582 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.67 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394083 | 1.00 | KDM4E (0.67) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL27634628 | 0.85 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL10402322 | 0.85 | HSP90AA1 (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30595872 | 0.84 | HSP90AA1 (0.52) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2814353 | 0.84 | HSP90AA1 (0.52) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1181563 | 0.82 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29351528 | 0.82 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29907716 | 0.82 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3711450 | 0.82 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5922 | 0.82 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434801-B | 4 '-pyridyl-pyrimidine class compounds of one kind and its synthetic method and application | 南京林业大学 | 2019-08-27 | — | — | CN | claimed |
| CN-107434801-A | A kind of 4 ' pyridyl-pyrimidine class compounds and its synthetic method and application | 南京林业大学 | 2017-12-05 | — | — | CN | claimed |
| EP-4504985-A1 | METHOD FOR HIGH AND SELECTIVE EXTRACTION OF A PRECIOUS METAL | Singapore Polytechnic (SG) | 2025-02-12 | — | — | EP | disclosed |
| CN-118922566-A | Method for extracting noble metal with high selectivity | 新加坡理工学院 | 2024-11-08 | — | — | CN | disclosed |
| WO-2023191722-A1 | METHOD FOR HIGH AND SELECTIVE EXTRACTION OF A PRECIOUS METAL | SINGAPORE POLYTECHNIC (SG) | 2023-10-05 | — | — | WO | disclosed |
| EP-4225310-A1 | HETEROARYL AMIDE INHIBITORS OF CD38 | Napa Therapeutics Ltd. (VG) | 2023-08-16 | — | — | EP | disclosed |
| US-11673100-B2 | Systems and methods for integrated solar photodialysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-13 | — | — | US | disclosed |
| US-11678498-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-06-13 | — | — | US | disclosed |
| US-11673100-B2 | Systems and methods for integrated solar photodialysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220332699-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. | 2022-10-20 | — | — | US | disclosed |
| WO-2022119501-A1 | METHOD FOR HIGH AND SELECTIVE EXTRACTION OF SILVER | SINGAPORE POLYTECHNIC (SG) | 2022-06-09 | — | — | WO | disclosed |
| WO-2006072426-A1 | ALKINYL-OXYPYRIMIDINE USED IN THE FORM OF PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | WO | disclosed |
| EP-1608375-A1 | METHODS FOR TREATING OR PREVENTING AN INFLAMMATORY OR METABOLIC CONDITION BY INHIBITING JNK | Signal Pharmaceuticals LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004084901-A1 | METHODS FOR TREATING OR PREVENTING AN INFLAMMATORY OR METABOLIC CONDITION BY INHIBITING JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040106634-A1 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC | 2004-06-03 | — | — | US | disclosed |
| CN-1246856-A | Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents | AMGEN INC (US) | 2000-03-08 | — | — | CN | disclosed |
| US-5304647-A | Addition of an organolithium reagent; dehydrogenation of addition product; two-phase conditions prevents hydrolysis | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| US-4963676-A | INTERMEDIATES FOR NOVEL UNFUSED HETEROBICYCLIC COMPOUNDS WITH BIOLOGICAL ACTIVITY; ANTICANCER AGENTS | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1990-10-16 | — | — | US | disclosed |
| US-4929726-A | ANTICARCINOGENIC AGENTS | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1990-05-29 | — | — | US | disclosed |
| WO-1989007599-A2 | NOVEL DIAZINES AND THEIR METHOD OF PREPARATION | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1989-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106634-A1 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | MAPK6, MAPKAPK2, DUSP6 | KDM4E 3645/4885LMNA 3512/4885CCR1 1075/4885 |
| US-20220332699-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | CYP46A1, CYP26A1, CYP21A2 | KDM4E 2676/4885LMNA 2357/4885CCR1 3046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.