Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17062986 | 0.98 | GSTK1 (0.55) | ALDH1A1GSTK1FFAR4FFAR1GPR84 | |
| SCHEMBL10698108 | 0.98 | GSTK1 (0.55) | ALDH1A1GSTK1FFAR4FFAR1GPR84 | |
| SCHEMBL8018732 | 0.94 | ALDH1A1 (0.58) | ALDH1A1GSTK1FFAR4FFAR1AKR1B1 | |
| Hexanoate SCHEMBL11509898 | 0.93 | FFAR4 (0.62) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| Adipic Acid SCHEMBL17817818 | 0.92 | ALDH1A1 (0.69) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| Sebacic Acid SCHEMBL17817821 | 0.90 | ALDH1A1 (0.67) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| Azelaic Acid SCHEMBL18043679 | 0.90 | ALDH1A1 (0.67) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| Sebacic Acid SCHEMBL30542922 | 0.90 | ALDH1A1 (0.67) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| SCHEMBL6691203 | 0.89 | GSTK1 (0.59) | ALDH1A1GSTK1FFAR4FFAR1AKR1B1 | |
| Stearic Acid SCHEMBL10277719 | 0.89 | ALDH1A1 (0.64) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193148-B2 | Short fatty acid tail polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-06-05 | — | — | US | disclosed |
| US-20090239792-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239792-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | TLR5, TLR3, TLR2 | ALDH1A1 4688/4885GSTK1 1686/4885FFAR4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.