Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 7/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131795 | 0.84 | MEN1 (0.52) | MEN1KMT2ANSD2NCOA1NCOA3 | |
| SCHEMBL23612900 | 0.73 | MEN1 (0.52) | MEN1KMT2ANSD2NCOA1NCOA3 | |
| SCHEMBL14140891 | 0.73 | MEN1 (0.54) | MEN1KMT2ANSD2NCOA1NCOA3 | |
| SCHEMBL6951880 | 0.71 | MEN1 (0.52) | MEN1KMT2AGSTP1GSTM2 | |
| SCHEMBL3063567 | 0.69 | MEN1 (0.52) | MEN1KMT2ANSD2NCOA1NCOA3 | |
| SCHEMBL26025 | 0.69 | MEN1 (0.49) | MEN1KMT2AGSTP1GSTM2ALDH1A1 | |
| SCHEMBL6123423 | 0.66 | MEN1 (0.51) | MEN1KMT2AGSTP1GSTM2ALDH1A1 | |
| SCHEMBL4553099 | 0.66 | GSTM2 (0.36) | MEN1KMT2AGSTP1GSTM2ALDH1A1 | |
| SCHEMBL26054240 | 0.65 | MEN1 (0.56) | MEN1KMT2AHCAR3GSTP1GSTM2 | |
| SCHEMBL13104327 | 0.64 | MEN1 (0.41) | MEN1KMT2AGSTP1GSTM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130302827-A1 | ANNEXIN-BASED APOPTOSIS MARKERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2013-11-14 | — | — | US | claimed |
| US-8541549-B2 | Annexin-based apoptosis markers | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-09-24 | — | — | US | claimed |
| US-20090246802-A1 | ANNEXIN-BASED APOPTOSIS MARKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-10-01 | — | — | US | claimed |
| US-20130302827-A1 | ANNEXIN-BASED APOPTOSIS MARKERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2013-11-14 | — | — | US | disclosed |
| US-8541549-B2 | Annexin-based apoptosis markers | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-09-24 | — | — | US | disclosed |
| US-20090246802-A1 | ANNEXIN-BASED APOPTOSIS MARKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-10-01 | — | — | US | disclosed |