Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782705 | 0.75 | PI4KA (0.56) | PARP1MEN1KMT2AMAPTGAA | |
| SCHEMBL30983935 | 0.74 | PIM1 (0.37) | PARP1GAAPI4KAPI4K2BPI4K2A | |
| SCHEMBL4295696 | 0.72 | KDM4E (0.39) | PARP1MEN1KMT2AMAPTGAA | |
| SCHEMBL2371989 | 0.71 | JAK2 (0.49) | JAK2TYK2 | |
| SCHEMBL5695310 | 0.69 | NPC1 (0.68) | MAPTGAAPOLBTDP1L3MBTL1 | |
| SCHEMBL783767 | 0.69 | PI4KA (0.50) | PARP1MEN1KMT2AMAPTGAA | |
| SCHEMBL783584 | 0.68 | PARP1 (0.53) | PARP1GAAKDM4EALDH1A1MGAM | |
| SCHEMBL2202986 | 0.67 | ALDH1A1 (0.43) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL783583 | 0.66 | PARP1 (0.47) | PARP1MEN1KMT2AMAPTGAA | |
| SCHEMBL30983897 | 0.66 | PIM1 (0.45) | CYP3A4CYP2C9PIM1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079000-A1 | IMIDAZOLOPYRIMIDINE MODULATORS OF TRPV1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |