Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783583 | 0.75 | PARP1 (0.47) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL783584 | 0.73 | PARP1 (0.53) | KDM4EALDH1A1GAAGFERPARP1 | |
| SCHEMBL4295694 | 0.72 | PARP1 (0.36) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL783767 | 0.72 | PI4KA (0.50) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL30440652 | 0.71 | RHEB (0.48) | KDM4EALDH1A1GAACHEK2PARP1 | |
| SCHEMBL29403371 | 0.67 | KIF11 (0.50) | MEN1ALDH1A1KMT2AHSD17B10GAA | |
| SCHEMBL349356 | 0.67 | KIF11 (0.50) | MEN1ALDH1A1KMT2AHSD17B10GAA | |
| SCHEMBL17290110 | 0.67 | TBK1 (0.47) | HTTPARP1 | |
| SCHEMBL15756742 | 0.67 | KDM4E (0.54) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL4846517 | 0.67 | GAA (0.39) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079000-A1 | IMIDAZOLOPYRIMIDINE MODULATORS OF TRPV1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |