Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL2971795 | 0.89 | SMN1; SMN2 (0.48) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL2950245 | 0.89 | SMN1; SMN2 (0.48) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL1293052 | 0.89 | SMN1; SMN2 (0.48) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL14722520 | 0.88 | SMN1; SMN2 (0.41) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL14722521 | 0.88 | SMN1; SMN2 (0.41) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL17786061 | 0.87 | KDM4E (0.50) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL10432218 | 0.87 | KDM4E (0.50) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL4441683 | 0.87 | SMN1; SMN2 (0.47) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL7773385 | 0.87 | KDM4E (0.50) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Benzimidazole SCHEMBL31239694 | 0.87 | SMN1; SMN2 (0.47) | PRKCIKDM4EMAPTRAD52MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751357-A | Benzimidazole substituted cyclopentenones compound, and preparation method and application thereof | 云南农业大学 | 2025-04-04 | — | — | CN | claimed |
| CN-117402464-A | Blue light-proof composite master batch | 上海沪正实业有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-109912580-A | A kind of Ratiometric fluorescent probe and its preparation method and application | 南华大学 | 2019-06-21 | — | — | CN | claimed |
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | claimed |
| JP-2007505085-A | — | — | 2007-03-08 | — | — | JP | claimed |
| EP-1667995-A1 | BENZIMIDAZOLE ACETONITRILES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-14 | — | — | EP | claimed |
| WO-2005026155-A1 | BENZIMIDAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |
| CN-119751357-A | Benzimidazole substituted cyclopentenones compound, and preparation method and application thereof | 云南农业大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-117402464-A | Blue light-proof composite master batch | 上海沪正实业有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-109912580-A | A kind of Ratiometric fluorescent probe and its preparation method and application | 南华大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912810-A | A kind of preparation method of porous ZIF-7 ball | 浙江工业大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912580-A | A kind of Ratiometric fluorescent probe and its preparation method and application | 南华大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-108250220-A | Phenothiazines coumarine dye and synthetic method with big Stokes displacements | 广西师范学院 | 2018-07-06 | — | — | CN | disclosed |
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | disclosed |
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | disclosed |
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | disclosed |
| EP-1667995-A1 | BENZIMIDAZOLE ACETONITRILES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-14 | — | — | EP | disclosed |
| EP-1667995-A1 | BENZIMIDAZOLE ACETONITRILES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026155-A1 | BENZIMIDAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |
| WO-2005026155-A1 | BENZIMIDAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203134-A1 | Benzimidazole Acetonitriles | PKD1, GPR119, CCNI | PRKCI 1530/4885KDM4E 3530/4885MAPT 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.