Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001752 | 0.83 | PRPS1 (0.53) | PRPS1GPR119 | |
| SCHEMBL4157433 | 0.71 | GPR119 (0.46) | GPR119 | |
| SCHEMBL31162930 | 0.67 | GPR119 (0.40) | GPR119 | |
| SCHEMBL26635909 | 0.66 | GPR119 (0.48) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL30670074 | 0.66 | GPR119 (0.48) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL30735317 | 0.66 | GPR119 (0.48) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL26619597 | 0.66 | GPR119 (0.48) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL30734968 | 0.66 | GPR119 (0.48) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL26619601 | 0.66 | GPR119 (0.48) | GPR119EEDRBBP4SUZ12EZH2 | |
| SCHEMBL26636977 | 0.64 | GPR119 (0.46) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |