SCHEMBL10425907

SCHEMBL10425907

NC(=O)Nc1ccccc1OCCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.54
KMT2A Q03164 2/20 0.51
SIRT2 Q8IXJ6 1/20 0.51
LMNA P02545 3/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50
NLRP1 Q9C000 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
POLB P06746 2/20 0.49
TSHR P16473 1/20 0.48
NR3C2 P08235 1/20 0.48
GAA P10253 3/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MCL1 Q07820 1/20 0.46
FFAR1 O14842 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4297414 0.84 BRD4 (0.74) BRD4SIRT2ALDH1A1MAPTHTT
SCHEMBL13652639 0.84 GAA (0.56) BRD4KMT2AHTTTDP1POLB
SCHEMBL10424485 0.81 PPIA (0.58) KMT2AMAPTNR3C2GAAL3MBTL1
SCHEMBL14055 0.81 CYP2C19 (0.55) BRD4KMT2ALMNAALDH1A1MAPT
SCHEMBL10748359 0.81 MAPT (0.72) KMT2ALMNAALDH1A1MAPTPKM
SCHEMBL27494909 0.81 LMNA (0.52) BRD4KMT2ALMNAALDH1A1MAPT
SCHEMBL11080891 0.81 ALDH1A1 (0.47) KMT2ALMNAALDH1A1MAPTPKM
SCHEMBL6838359 0.79 KMT2A (0.68) KMT2ALMNAALDH1A1MAPTPKM
SCHEMBL13721 0.79 MTNR1A (0.53) BRD4KMT2ALMNAALDH1A1MAPT
SCHEMBL4933797 0.78 SIRT2 (0.49) BRD4KMT2ASIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4959092-A Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1990-09-25 US disclosed
EP-0293839-A2 Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1988-12-07 EP disclosed