SCHEMBL429778

SCHEMBL429778

CCCc1ccc(S(N)(=O)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 1.00
SMN1; SMN2 Q16637 1/20 0.78
CA1 P00915 11/20 0.67
CA9 Q16790 9/20 0.67
CA12 O43570 6/20 0.67
CA4 P22748 4/20 0.67
CA6 P23280 4/20 0.67
CA5A P35218 4/20 0.67
CA7 P43166 4/20 0.67
CA14 Q9ULX7 4/20 0.67
CA5B Q9Y2D0 4/20 0.67
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.57
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607623 0.88 CA2 (1.00) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL607046 0.86 CA2 (1.00) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL9126817 0.84 CA2 (0.96) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL10661919 0.84 CA2 (0.96) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL17817182 0.84 CA2 (0.96) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL28640316 0.84 CA2 (0.96) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL78265 0.84 CA2 (0.96) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL7898294 0.84 CA2 (0.96) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL16129968 0.83 CA2 (0.70) CA2SMN1; SMN2CA1CA9CA12
SCHEMBL18122304 0.83 CA2 (0.89) CA2SMN1; SMN2CA1CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
WO-2024048615-A1 METHOD FOR PRODUCING QUINOXALINE DERIVATIVE 協和キリン株式会社 2024-03-07 WO claimed
CN-113527152-A Biphenylsulfonamide compound and method for preventing and treating crop pests by using same 西北农林科技大学 2021-10-22 CN claimed
US-10201957-B2 Dye receiving layer composition, dye receiving substrate and method of fabricating the same CHIEN HWA COATING TECHNOLOGY , INC. (TW) 2019-02-12 US claimed
EP-3363650-A1 DYE RECEIVING LAYER COMPOSITION, DYE RECEIVING SUBSTRATE AND METHOD OF FABRICATING THE SAME Chien Hwa Coating Technology, Inc. (TW) 2018-08-22 EP claimed
CN-102802416-A Fungicidal mixtures BASF SE 2012-11-28 CN claimed
CN-102595903-A Fungicidal mixtures BASF SE 2012-07-18 CN claimed
CN-102458124-A Fungicidal mixtures BASF SE 2012-05-16 CN claimed
EP-2097414-A1 PYRROLO [2, 3-B]PYRIDINE DERIVATIVES AS KINASE MODULATORS PLEXXIKON, INC. (US) 2009-09-09 EP claimed
WO-2008079906-A1 PYRROLO [2, 3-B] PYRIDINE DERIVATIVES AS KINASE MODULATORS PLEXXIKON, INC. (US) 2008-07-03 WO claimed
EP-1805442-A2 HYDROLYSIS RESISTANT POLYAMIDE COMPOSITIONS AND ARTICLES FORMED THEREFROM E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-07-11 EP claimed
WO-2006047775-A2 HYDROLYSIS RESISTANT POLYAMIDE COMPOSITIONS AND ARTICLES FORMED THEREFROM E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-04 WO claimed
CN-1177832-C Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion ���ĵ�˹ҩƷ�¹��ɷ����޹�˾ 2004-12-01 CN claimed
US-20020065271-A1 Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion PEYMAN ANUSCHIRWAN (DE) 2002-05-30 US claimed
US-6313119-B1 VITRONECTIN RECEPTOR ANTAGONISTS ADVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-11-06 US claimed
CN-1293662-A Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion AIWENTIS DRUG DEUTSCHLAND GMBH (DE) 2001-05-02 CN claimed
EP-1049677-A1 NOVEL SULFONAMIDE DERIVATIVES AS INHIBITORS OF BONE RESORPTION AND AS INHIBITORS OF CELL ADHESION Aventis Pharma Deutschland GmbH (DE) 2000-11-08 EP claimed
WO-1999037621-A1 NOVEL SULFONAMIDE DERIVATIVES AS INHIBITORS OF BONE RESORPTION AND AS INHIBITORS OF CELL ADHESION AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 1999-07-29 WO claimed
CN-119954826-A Compound, preparation method and application thereof, lithium ion battery electrolyte additive and electrolyte 华鼎国联动力电池有限公司 2025-05-09 CN disclosed
US-4792628-A ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065271-A1 Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion SOST, SELPLG, BST2 CA2 667/4885SMN1; SMN2 2971/4885CA1 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.