Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523236 | 0.74 | KCNH2 (0.35) | DHODHKCNH2SCN5A | |
| SCHEMBL3524695 | 0.73 | KCNH2 (0.35) | KCNH2SCN5A | |
| SCHEMBL13760545 | 0.72 | KCNH2 (0.34) | KCNH2SCN5A | |
| SCHEMBL3602001 | 0.70 | KCNH2 (0.33) | KCNH2SCN5A | |
| SCHEMBL14372289 | 0.65 | KCNH2 (0.36) | KCNH2SCN5A | |
| SCHEMBL12013041 | 0.61 | BRD4 (0.38) | — | |
| SCHEMBL14372255 | 0.61 | POLB (0.38) | — | |
| SCHEMBL9377590 | 0.60 | KCNH2 (0.39) | KCNH2SCN5A | |
| SCHEMBL30813123 | 0.59 | PREP (0.48) | — | |
| SCHEMBL30813103 | 0.58 | PREP (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252810-B2 | Bicycloamine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20090270369-A1 | BICYCLOAMINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270369-A1 | BICYCLOAMINE DERIVATIVES | SCN1B, KCNJ2, KCNH2 | DHODH 3831/4885KCNH2 3/4885SCN5A 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.