Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524695 | 0.81 | KCNH2 (0.35) | KCNH2SCN5A | |
| SCHEMBL3602001 | 0.80 | KCNH2 (0.33) | KCNH2SCN5A | |
| SCHEMBL3523236 | 0.79 | KCNH2 (0.35) | KCNH2SCN5A | |
| SCHEMBL4298007 | 0.72 | DHODH (0.32) | KCNH2SCN5A | |
| SCHEMBL14372289 | 0.69 | KCNH2 (0.36) | KCNH2SCN5A | |
| SCHEMBL9377590 | 0.66 | KCNH2 (0.39) | KCNH2SCN5A | |
| SCHEMBL3521622 | 0.65 | KCNH2 (0.77) | KCNH2SCN5A | |
| SCHEMBL14372255 | 0.64 | POLB (0.38) | — | |
| SCHEMBL30813206 | 0.63 | MMP2 (0.32) | — | |
| SCHEMBL3524929 | 0.63 | KCNH2 (0.42) | KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009101917-A1 | BICYCLOAMINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-08-20 | — | — | WO | disclosed |