Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779757 | 0.84 | ATM (0.47) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5779754 | 0.84 | ATM (0.47) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27621790 | 0.81 | ATM (0.51) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4214722 | 0.81 | HTT (0.55) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL30011680 | 0.81 | ATM (0.68) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL40617 | 0.81 | ATM (0.68) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL9551091 | 0.79 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL5780275 | 0.79 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL27850229 | 0.79 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| Xanthene Carboxylic Acid SCHEMBL27368945 | 0.79 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011963-A1 | TRUCK FLEET FUEL ECONOMY BY THE USE OF OPTIMIZED ENGINE OIL, TRANSMISSION FLUID, AND GEAR OIL | AFTON CHEMICAL CORPORATION | 2009-01-08 | — | — | US | disclosed |
| CN-101228158-A | N-amide derivatives of 8-azabicyclo[3.2.1]oct-3-yl as ccr1 antagonists | ALMIRALL LAB (ES) | 2008-07-23 | — | — | CN | disclosed |
| US-5703023-A | VINYLAROMATIC-MALEIC ESTER POLYMERIC VISCOSITY INDEX IMPROVER | ETHYL CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5652201-A | INCLUDING OIL-SOLUBLE OVERBASED ALKALINE EARTH METAL-CONTAINING SULFONATE DETERGENT, BORON-FREE ADDITIVE FORMED BY HEATING ASHLESS DISPERSANT CONTAINING BASIC NITROGEN AND/OR HYDROXYL GROUP WITH INORGANIC PHOSPHORUS ACID | ETHYL PETROLEUM ADDITIVES INC. (US) | 1997-07-29 | — | — | US | disclosed |
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | disclosed |
| US-5498355-A | CRANKCASE OIL DISPERSANT, A FIRST SUCCINYLATED POLYALKYLENE REACTED WITH AN ALKYLENE POLYAMINE AND A SECOND REACTED WITH A HYDROXYPROPYLATED ALKYLENE POLYAMINE | ETHYL CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |
| EP-0516461-B1 | Lubricating oil compositions and concentrates and the use thereof | ETHYL PETROLEUM ADDITIVES INC (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0492934-B1 | Lubricating oil compositions and concentrates and the use thereof | ETHYL PETROLEUM ADDITIVES INC (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0516461-A1 | Lubricating oil compositions and concentrates and the use thereof | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0493928-A1 | Lubricating oil compositions, concentrates and the use thereof | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0492934-A1 | Lubricating oil compositions and concentrates and the use thereof | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-4162985-A | HYDROGENATED VINYLARENE-CONJUGATED DIENE POLYMER, EXTREME PRESSURE COMPONENT, OIL BASE | THE LUBRIZOL CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |