Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14249311 | 0.86 | ATM (0.68) | HTTTP53ATMLMNASMN1; SMN2 | |
| SCHEMBL10579059 | 0.85 | HTT (0.52) | HTTTP53ATMLMNASMN1; SMN2 | |
| Potassium Ion SCHEMBL10978488 | 0.85 | HTT (0.52) | HTTTP53ATMLMNASMN1; SMN2 | |
| SCHEMBL27621790 | 0.81 | ATM (0.51) | HTTTP53ATMLMNASMN1; SMN2 | |
| SCHEMBL4298019 | 0.81 | ATM (0.56) | HTTTP53ATMLMNASMN1; SMN2 | |
| SCHEMBL8817282 | 0.81 | HTT (0.55) | HTTTP53ATMLMNASMN1; SMN2 | |
| Xanthene Carboxylic Acid SCHEMBL30011680 | 0.81 | ATM (0.68) | HTTTP53ATMLMNASMN1; SMN2 | |
| Xanthene Carboxylic Acid SCHEMBL40617 | 0.81 | ATM (0.68) | HTTTP53ATMLMNASMN1; SMN2 | |
| SCHEMBL5753228 | 0.81 | TSHR (0.51) | HTTTP53ATMLMNASMN1; SMN2 | |
| SCHEMBL5753223 | 0.81 | TSHR (0.51) | HTTTP53ATMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155185-A1 | MEDICAMENTS FOR INHALATION COMPRISING AN ANTICHOLINERGIC AND A BETAMIMETIC | MEADE CHRISTOPHER JOHN MONTAGUE | 2009-06-18 | — | — | US | disclosed |
| US-20050025718-A1 | Medicaments for inhalation comprising an anticholinergic and a betamimetic | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-03 | — | — | US | disclosed |
| US-6696462-B2 | CYCLOPROPYLTROPINE CARBOXYLATE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |
| US-20030207912-A1 | Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH. CO. KG (DE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155185-A1 | MEDICAMENTS FOR INHALATION COMPRISING AN ANTICHOLINERGIC AND A BETAMIMETIC | ADRB2, CHRM3, ADRB1 | HTT 4455/4885TP53 3804/4885ATM 3747/4885 |
| US-20030207912-A1 | Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions | CHRM1, CHRNA1, CHRNB1 | HTT 1057/4885TP53 4812/4885ATM 4488/4885 |
| US-20050025718-A1 | Medicaments for inhalation comprising an anticholinergic and a betamimetic | ADRB2, CHRM3, ADRB1 | HTT 4455/4885TP53 3804/4885ATM 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.