Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633250 | 0.92 | KDM4E (0.68) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL13932580 | 0.90 | DYRK1A (0.57) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL1996999 | 0.89 | APP (0.73) | SMN1; SMN2KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL2136576 | 0.86 | APP (0.69) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL2117508 | 0.85 | MMP13 (0.60) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL3196637 | 0.84 | APP (0.62) | SMN1; SMN2KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL10032126 | 0.84 | MAPT (0.70) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL4301852 | 0.84 | KMT2A (0.54) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL2628260 | 0.83 | APP (0.73) | SMN1; SMN2KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL9797268 | 0.81 | KDM4E (0.88) | SMN1; SMN2KDM4ENFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | claimed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |