Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 2/20 | 0.49 |
| ▸ | RARG | P13631 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932580 | 0.84 | DYRK1A (0.57) | KMT2ARAB9AGAASMN1; SMN2HTT | |
| SCHEMBL4298752 | 0.84 | SMN1; SMN2 (0.60) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL7604821 | 0.82 | NPC1 (0.61) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL2380048 | 0.82 | SMN1; SMN2 (0.59) | KMT2AMEN1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1996999 | 0.81 | APP (0.73) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL14872038 | 0.81 | NPC1 (0.62) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL146339 | 0.79 | SMN1; SMN2 (0.69) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL11973310 | 0.79 | APP (0.63) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL2633250 | 0.79 | KDM4E (0.68) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL4298781 | 0.79 | RARA (0.64) | KMT2AMEN1RAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |