Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 18/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 18/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 17/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299553 | 0.88 | PDE10A (0.38) | PDE1APDE1BPDE1CTLR8TLR7 | |
| SCHEMBL4824309 | 0.84 | TLR7 (0.40) | TLR8TLR7 | |
| SCHEMBL4302529 | 0.83 | TLR7 (0.47) | TLR8TLR7HSP90AA1HSP90AB1 | |
| SCHEMBL4298976 | 0.80 | TLR7 (0.38) | PDE1APDE1BPDE1CTLR8TLR7 | |
| SCHEMBL4305882 | 0.79 | TLR7 (0.38) | TLR8TLR7 | |
| SCHEMBL13663019 | 0.79 | PDE1B (0.42) | PDE1APDE1BPDE1CTLR7 | |
| SCHEMBL4296333 | 0.76 | TLR7 (0.34) | PDE1APDE1BPDE1CTLR8TLR7 | |
| SCHEMBL3353822 | 0.76 | AVPR1A (0.43) | TLR8TLR7 | |
| SCHEMBL1895061 | 0.75 | TLR7 (0.56) | TLR8TLR7 | |
| SCHEMBL4310319 | 0.75 | TLR8 (0.39) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | IL2, IL4I1, IFNG | PDE1A 2601/4885PDE1B 3396/4885PDE1C 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.