SCHEMBL430003

SCHEMBL430003

CCCCCCCCCCCCCCCC[CH]N1CCCC1=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
MGLL Q99685 3/20 0.41
FAAH O00519 2/20 0.41
TSHR P16473 1/20 0.36
BRD4 O60885 1/20 0.35
BRD2 P25440 1/20 0.35
GAA P10253 1/20 0.34
NAAA Q02083 1/20 0.34
TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803804 0.83 FAAH (0.45) ALOX5MGLLFAAHTSHRTRPV1
SCHEMBL18935701 0.83 FAAH (0.45) ALOX5MGLLFAAHTSHRTRPV1
SCHEMBL7803803 0.83 FAAH (0.45) ALOX5MGLLFAAHTSHRTRPV1
SCHEMBL18935700 0.83 FAAH (0.45) ALOX5MGLLFAAHTSHRTRPV1
SCHEMBL7794085 0.81 FAAH (0.46) ALOX5MGLLFAAHTRPV1
SCHEMBL7794084 0.81 FAAH (0.46) ALOX5MGLLFAAHTRPV1
SCHEMBL786722 0.81 TSHR (0.48) ALOX5MGLLFAAHTSHR
SCHEMBL3674032 0.81 TSHR (0.48) ALOX5MGLLFAAHTSHR
SCHEMBL27601371 0.81 TSHR (0.48) ALOX5MGLLFAAHTSHR
SCHEMBL787107 0.81 TSHR (0.48) ALOX5MGLLFAAHTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019109243-A1 Cosmetic composition for permanently changing the shape of keratinous fibers HENKEL AG & CO.KGAA (DE) 2019-06-13 WO disclosed
EP-2393469-B1 Process of treating hair RHODIA OPERATIONS (FR) 2016-10-12 EP disclosed
US-20120021025-A1 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2012-01-26 US disclosed
WO-2010089228-A9 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2011-04-21 WO disclosed
WO-2010089228-A1 AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS (FR) 2010-08-12 WO disclosed
EP-2216010-A1 Aqueous composition suitable as shampoo Rhodia Opérations (FR) 2010-08-11 EP disclosed
US-20060110379-A1 Linkage of agents using microparticles PERICOR SCIENCE, INC. (US) 2006-05-25 US disclosed
US-20060104966-A1 Transglutaminase linkage of agents to tissue PERICOR SCIENCE, INC. (US) 2006-05-18 US disclosed
US-6958148-B1 Linkage of agents to body tissue using microparticles and transglutaminase PERICOR SCIENCE, INC. (US) 2005-10-25 US disclosed
WO-2005092273-A2 METHOD OF COMPATIBILIZING CATIONIC MATERIALS WITH ANIONIC POLYMERS NOVEON IP HOLDINGS CORP. (US) 2005-10-06 WO disclosed
EP-1534221-A1 COMPOSITIONS OF ANIONIC POLYMERIC RHEOLOGY MODIFIERS AND CATIONIC MATERIALS Noveon IP Holdings Corp. (US) 2005-06-01 EP disclosed
US-20040170587-A1 Method of compatibilizing cationic materials with anionic polymers LUBRIZOL ADVANCED MATERIALS, INC. 2004-09-02 US disclosed
WO-2004026271-A1 COMPOSITIONS OF ANIONIC POLYMERIC RHEOLOGY MODIFIERS AND CATIONIC MATERIALS NOVEON IP HOLDINGS CORP. (US) 2004-04-01 WO disclosed
US-20040052748-A1 Compositions of anionic polymeric rheology modifiers and cationic materials LUBRIZOL ADVANCED MATERIALS, INC. 2004-03-18 US disclosed
EP-1303260-A2 LINKAGE OF AGENTS USING MICROPARTICLES Pericor Science, Inc. (US) 2003-04-23 EP disclosed
EP-1203141-A1 LINKAGE OF AGENTS TO TISSUE Pericor Science, Inc. (US) 2002-05-08 EP disclosed
EP-1202706-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE Pericor Science, Inc. (US) 2002-05-08 EP disclosed
WO-2002007707-A2 LINKAGE OF AGENTS USING MICROPARTICLES PERICOR SCIENCE, INC. (US) 2002-01-31 WO disclosed
WO-2001007009-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
WO-2001006829-A2 LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170587-A1 Method of compatibilizing cationic materials with anionic polymers PARN, PARG, PICALM ALOX5 3116/4885MGLL 2798/4885FAAH 4478/4885
US-20040052748-A1 Compositions of anionic polymeric rheology modifiers and cationic materials PBRM1, PARG, PARN ALOX5 2091/4885MGLL 1398/4885FAAH 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.