Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008717 | 0.89 | HRH4 (0.51) | HRH4 | |
| SCHEMBL4440410 | 0.83 | HRH4 (0.48) | HRH4 | |
| SCHEMBL604409 | 0.82 | HRH4 (0.55) | HRH4KCNH2 | |
| SCHEMBL602354 | 0.77 | HRH4 (0.57) | HRH4KCNH2 | |
| SCHEMBL602283 | 0.75 | HRH4 (0.55) | HRH4KCNH2 | |
| SCHEMBL4436591 | 0.75 | HRH4 (0.40) | HRH4 | |
| SCHEMBL605460 | 0.74 | HRH4 (0.56) | HRH4KCNH2 | |
| SCHEMBL4169731 | 0.74 | HRH4 (0.46) | HRH4KCNH2 | |
| SCHEMBL605371 | 0.74 | HRH4 (0.57) | HRH4KCNH2 | |
| SCHEMBL605607 | 0.73 | HRH4 (0.53) | HRH4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |