Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300322 | 0.83 | HRH4 (0.48) | HRH4 | |
| SCHEMBL603509 | 0.83 | HRH4 (0.55) | HRH4 | |
| SCHEMBL4008717 | 0.78 | HRH4 (0.51) | HRH4 | |
| SCHEMBL605114 | 0.76 | HRH4 (0.57) | HRH4 | |
| SCHEMBL4436591 | 0.74 | HRH4 (0.40) | HRH4 | |
| SCHEMBL606086 | 0.72 | HRH4 (0.55) | HRH4 | |
| SCHEMBL603797 | 0.71 | HRH4 (0.67) | HRH4 | |
| SCHEMBL601582 | 0.71 | HRH4 (0.58) | HRH4 | |
| SCHEMBL602350 | 0.71 | HRH4 (0.62) | HRH4 | |
| SCHEMBL603380 | 0.70 | HRH4 (0.57) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |