Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 12/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605808 | 0.84 | HRH4 (0.47) | HRH4SSTR5TNKSPARP1TNKS2 | |
| SCHEMBL4300322 | 0.75 | HRH4 (0.48) | HRH4 | |
| SCHEMBL603553 | 0.74 | SSTR5 (0.39) | HRH4SSTR5TNKSTNKS2 | |
| SCHEMBL4440410 | 0.74 | HRH4 (0.48) | HRH4 | |
| SCHEMBL603380 | 0.73 | HRH4 (0.57) | HRH4 | |
| SCHEMBL4008717 | 0.70 | HRH4 (0.51) | HRH4 | |
| SCHEMBL604421 | 0.69 | HRH4 (0.51) | HRH4 | |
| SCHEMBL602726 | 0.69 | HRH4 (0.47) | HRH4SSTR5TNKSPARP1TNKS2 | |
| SCHEMBL604091 | 0.67 | HRH4 (0.39) | HRH4 | |
| SCHEMBL4433307 | 0.66 | HRH4 (0.36) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |