Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527456 | 0.77 | POLB (0.42) | POLBMAPTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4772531 | 0.76 | POLB (0.41) | POLBMAPTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4776148 | 0.76 | POLB (0.44) | POLBMAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4723179 | 0.76 | POLB (0.41) | POLBMAPTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13939169 | 0.76 | POLB (0.41) | POLBMAPTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL3172845 | 0.76 | POLB (0.42) | POLBMAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL2059190 | 0.75 | POLB (0.46) | POLBMAPTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4776141 | 0.75 | POLB (0.43) | POLBMAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL563117 | 0.75 | POLB (0.38) | POLBMAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL5027849 | 0.75 | POLB (0.35) | POLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. | 2009-10-29 | — | — | US | disclosed |
| WO-2006026760-A2 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | IL2, IL4I1, IFNG | POLB 1638/4885MAPT 3772/4885MAPK1 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.